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Cardiac Imaging

E3010. T1 Mapping in Cardiooncologic Imaging

Deaderick S1,  Gage K2,  Jeong D.2 1. University of South Florida, Tampa, FL; 2. Moffitt Cancer Center, Tampa, FL

Address correspondence to S. Deaderick (sdeaderick@health.usf.edu)

Background Information: T1 mapping is an imaging technique that utilizes unenhanced native T1 and contrast-enhanced extracellular volume (ECV) fraction quantification. T1 mapping offers quantitative analysis of myocardium and potentially other structures in the otherwise qualitative conventional cardiac MR (CMR) examination. The myocardium can be divided into myocytes and the surrounding interstitium. Native T1 mapping reflects myocardial disease involving both compartments while using gadolinium based contrast agent allows for calculating ECV fraction and assessing for interstitial disease. The purpose of this exhibit is to review the current clinical applications of T1 mapping in CMR and discuss the specific role of T1 mapping in cardiooncologic imaging.

Educational Goals/Teaching Points: We familiarize the reader with the basics of T1 mapping, review current clinical applications of T1 mapping in CMR, discuss the potential role of T1 mapping in cardiooncologic imaging, and explore other possible applications of T1 mapping in CMR.

Key Anatomic/Physiologic Issues and Imaging Findings/Techniques: The imaging technique of T1 mapping will be discussed in the setting of cardiac MRI. The exhibit will review applications and discuss reliability of T1 mapping in diagnosing oncologic related conditions for which a patient is referred for CMR. The exhibit will also focus on the emerging applications of T1 mapping in cardiooncologic imaging, such as differentiating tumor from thrombus, particularly when IV gadolinium is contraindicated. Additional pathophysiologic issues to be discussed include cardiac amyloidosis, anthracycline toxicity, and other infiltrative myocardial processes.

Conclusion: Following review of this exhibit the reader will have a better understanding of the fundamentals of T1 mapping and how T1 mapping can be used to image various cardiac conditions with an emerging use in cardiooncologic imaging.